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Optimal Partitioning for Linear Mixed Effects Models: Applications to Identifying Placebo Responders

A long–standing problem in clinical research is distinguishing drug treated subjects that respond due to specific effects of the drug from those that respond to non-specific (or placebo) effects of the treatment. Linear mixed effect models are commonly used to model longitudinal clinical trial data....

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Autors principals: Tarpey, Thaddeus, Petkova, Eva, Lu, Yimeng, Govindarajulu, Usha
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007089/
https://ncbi.nlm.nih.gov/pubmed/21494314
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