Mechanism for Multiple Ligand Recognition by the Human Transferrin Receptor

Transferrin receptor 1 (TfR) plays a critical role in cellular iron import for most higher organisms. Cell surface TfR binds to circulating iron-loaded transferrin (Fe-Tf) and transports it to acidic endosomes, where low pH promotes iron to dissociate from transferrin (Tf) in a TfR-assisted process....

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Veröffentlicht in:	PLoS Biol
Hauptverfasser:	Giannetti, Anthony M, Snow, Peter M, Zak, Olga, Björkman, Pamela J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	PLOS 2003
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14691533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0000051
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