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Diversity of Opioid Requirements for Postoperative Pain Control Following Oral Surgery—Is It Affected by Polymorphism of the μ-Opioid Receptor?

We experience individual differences in pain and sensitivity to analgesics clinically. Genetic factors are known to influence individual difference. Polymorphisms in the human OPRM1 gene, which encodes the μ-opioid receptors, may be associated with the clinical effects of opioid analgesics. The purp...

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Detalhes bibliográficos
Main Authors: Fukuda, Ken-ichi, Hayashida, Masakazu, Ikeda, Kazutaka, Koukita, Yoshihiko, Ichinohe, Tatsuya, Kaneko, Yuzuru
Formato: Artigo
Idioma:Inglês
Publicado em: The American Dental Society of Anesthesiology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006662/
https://ncbi.nlm.nih.gov/pubmed/21174568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2344/0003-3006-57.4.145
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