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Crystal structure of the phage T4 recombinase UvsX and its functional interaction with the T4 SF2 helicase UvsW

Bacteriophage T4 provides an important model system for studying the mechanism of homologous recombination. We have determined the crystal structure of the T4 UvsX recombinase, and the overall architecture and fold closely resembles that of RecA, including a highly conserved ATP binding site. Based...

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Detalhes bibliográficos
Main Authors: Gajewski, Stefan, Webb, Michael R., Galkin, Vitold, Egelman, Edward H., Kreuzer, Kenneth N., White, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006652/
https://ncbi.nlm.nih.gov/pubmed/21035462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.004
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