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DNA condensation by TmHU studied by optical tweezers, AFM and molecular dynamics simulations

The compaction of DNA by the HU protein from Thermotoga maritima (TmHU) is analysed on a single-molecule level by the usage of an optical tweezers-assisted force clamp. The condensation reaction is investigated at forces between 2 and 40 pN applied to the ends of the DNA as well as in dependence on...

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Bibliografiska uppgifter
Huvudupphovsmän: Wagner, Carolin, Olbrich, Carsten, Brutzer, Hergen, Salomo, Mathias, Kleinekathöfer, Ulrich, Keyser, Ulrich F., Kremer, Friedrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006463/
https://ncbi.nlm.nih.gov/pubmed/22210966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-010-9203-7
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