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Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma
Nitric oxide (NO), formed by nitric oxide synthase (NOS), is an important mediator of lung inflammation in allergic asthma. Asymmetric dimethylarginine (ADMA), a competitive endogenous inhibitor of NOS, is metabolized by the enzyme dimethylarginine dimethylaminohydrolase (DDAH). Elevated ADMA has be...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006265/ https://ncbi.nlm.nih.gov/pubmed/20889675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00188.2010 |
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