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Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure

Glucagon-like peptide-2 (GLP-2) is a nutrient-dependent, proglucagon-derived hormone that is a proposed treatment for human short bowel syndrome (SBS). The objective was to determine how the timing, duration, and cessation of GLP-2 administration affect intestinal adaptation and enterocyte kinetics...

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Detalhes bibliográficos
Main Authors: Koopmann, Matthew C., Chen, Xueyan, Holst, Jens J., Ney, Denise M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006245/
https://ncbi.nlm.nih.gov/pubmed/20864657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00367.2010
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