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A composite likelihood approach to the analysis of longitudinal clonal data on multitype cellular systems under an age-dependent branching process

A recurrent statistical problem in cell biology is to draw inference about cell kinetics from observations collected at discrete time points. We investigate this problem when multiple cell clones are observed longitudinally over time. The theory of age-dependent branching processes provides an appea...

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Detalhes bibliográficos
Main Authors: Chen, Rui, Hyrien, Ollivier, Noble, Mark, Mayer-Pröschel, Margot
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006127/
https://ncbi.nlm.nih.gov/pubmed/20732974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq050
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