Effects of an Alpha 7-Nicotinic Agonist on Default Network Activity in Schizophrenia

BACKGROUND: 3-(2,4-Dimethoxybenzylidene)-anabaseine (DMXB-A) is a partial agonist at α7 nicotinic acetylcholine receptors that has been evaluated clinically for treatment of schizophrenia. The current study examined the effects of DMXB-A on default network activity as a biomarker for drug effects on...

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Main Authors: Tregellas, Jason R., Tanabe, Jody, Rojas, Donald C., Shatti, Shireen, Olincy, Ann, Johnson, Lynn, Martin, Laura F., Soti, Ferenc, Kem, William R., Leonard, Sherry, Freedman, Robert
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005969/
https://ncbi.nlm.nih.gov/pubmed/20728875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.07.004
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