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Divalent Metal- and High Mobility Group N Protein-Dependent Nucleosome Stability and Conformation

High mobility group N proteins (HMGNs) bind specifically to the nucleosome core and act as chromatin unfolding and activating factors. Using an all-Xenopus system, we found that HMGN1 and HMGN2 binding to nucleosomes results in distinct ion-dependent conformation and stability. HMGN2 association wit...

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Autors principals: Ong, Michelle S., Vasudevan, Dileep, Davey, Curt A.
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005839/
https://ncbi.nlm.nih.gov/pubmed/21188164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/143890
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