Loading...

Predicting memapsin 2 (β-secretase) hydrolytic activity

Memapsin 2 (BACE1, β-secretase), a membrane aspartic protease, functions in the cleavage of brain β-amyloid precursor protein (APP) leading to the production of β-amyloid. Because the excess level of β-amyloid in the brain is a leading factor in Alzheimer's disease (AD), memapsin 2 is a major t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Li, Xiaoman, Bo, Huang, Zhang, Xuejun C, Hartsuck, Jean A, Tang, Jordan
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005788/
https://ncbi.nlm.nih.gov/pubmed/20853423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.502
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!