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Experimental optimization of protein refolding with a genetic algorithm
Refolding of proteins from solubilized inclusion bodies still represents a major challenge for many recombinantly expressed proteins and often constitutes a major bottleneck. As in vitro refolding is a complex reaction with a variety of critical parameters, suitable refolding conditions are typicall...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3005780/ https://ncbi.nlm.nih.gov/pubmed/20799347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.488 |
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