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A novel liposome-based therapy to reduce complement-mediated injury in revascularized tissues

BACKGROUND: Ischemia/reperfusion (IR) injury is an unavoidable consequence of tissue transplantation or replantation that often leads to inflammation and cell death. Excessive complement activation following IR induces endothelial cell injury, altering vascular and endothelial barrier function causi...

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Detalhes bibliográficos
Main Authors: Goga, Ledia, Pushpakumar, Sathnur B., Perez-Abadia, Gustavo, Olson, Paul, Anderson, Gary, Soni, Chirag V., Barker, John H., Maldonado, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005705/
https://ncbi.nlm.nih.gov/pubmed/21074780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.09.033
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