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Angiotensin-converting enzymes and drug discovery in cardiovascular diseases

Angiotensin-converting enzyme (ACE) is a major target in the treatment of cardiovascular diseases (CVDs). In addition to ACE, ACE2 – which is a homolog of ACE and promotes the degradation of angiotensin II (AngII) to Ang (1–7) – has been recognized recently as a potential therapeutic target in the m...

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Detalhes bibliográficos
Main Authors: Shi, Lijun, Mao, Caiping, Xu, Zhice, Zhang, Lubo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005694/
https://ncbi.nlm.nih.gov/pubmed/20170743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.02.003
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