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TACROLIMUS PRETREATMENT ATTENUATES PREEXISTING XENOSPECIFIC IMMUNITY AND ABROGATES HYPERACUTE REJECTION IN A PRESENSITIZED HAMSTER TO RAT LIVER TRANSPLANT MODEL

In the hamster to rat liver transplant model, we determined the efficacy of tacrolimus in attenuating natural xenospecific humoral immunity and in abrogating the hyperacute liver rejection that is produced by presensitizing the Lewis rat recipient. Hamster livers, transplanted orthotopically into na...

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Detalhes bibliográficos
Main Authors: Tsugita, Masashi, Valdivia, Luis A., Rao, Abdul S., Pan, Fan, Celli, Susanna, Demetris, Anthony J., Fung, John J., Starzl, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005620/
https://ncbi.nlm.nih.gov/pubmed/8685952
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