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Notch regulates numb: integration of conditional and autonomous cell fate specification

The Notch cell-cell signaling pathway is used extensively in cell fate specification during metazoan development. In many cell lineages, the conditional role of Notch signaling is integrated with the autonomous action of the Numb protein, a Notch pathway antagonist. During Drosophila sensory bristle...

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Bibliographic Details
Main Authors: Rebeiz, Mark, Miller, Steven W., Posakony, James W.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005598/
https://ncbi.nlm.nih.gov/pubmed/21148185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.050161
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