Variant ABO Blood Group Alleles, Secretor Status and Risk of Pancreatic Cancer: Results from the Pancreatic Cancer Cohort Consortium

BACKGROUND: Subjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A(1) versus A(2) variant, while O01 and O02 variants are nonfunctioning. We hypothesized: (1) A(1) allele would confer greater risk than A(2) allele, (2)...

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Autors principals: Wolpin, Brian M., Kraft, Peter, Xu, Mousheng, Steplowski, Emily, Olsson, Martin L., Arslan, Alan A., Bueno-de-Mesquita, H. Bas, Gross, Myron, Helzlsouer, Kathy, Jacobs, Eric J., LaCroix, Andrea, Petersen, Gloria, Stolzenberg-Solomon, Rachael Z., Zheng, Wei, Albanes, Demetrius, Allen, Naomi E., Amundadottir, Laufey, Austin, Melissa A., Boutron-Ruault, Marie-Christine, Buring, Julie E., Canzian, Federico, Chanock, Stephen J., Gaziano, J. Michael, Giovannucci, Edward L., Hallmans, Göran, Hankinson, Susan E., Hoover, Robert N., Hunter, David J., Hutchinson, Amy, Jacobs, Kevin B., Kooperberg, Charles, Mendelsohn, Julie B., Michaud, Dominique S., Overvad, Kim, Patel, Alpa V., Sanchéz, Maria-José, Sansbury, Leah, Shu, Xiao-Ou, Slimani, Nadia, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Vineis, Paolo, Visvanathan, Kala, Virtamo, Jarmo, Wactawski-Wende, Jean, Watters, Joanne, Yu, Kai, Zeleniuch-Jacquotte, Anne, Hartge, Patricia, Fuchs, Charles S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005538/
https://ncbi.nlm.nih.gov/pubmed/20971884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0751
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