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Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery

The rapid formation of numerous tissues during development is highly dependent on the swift activation of key developmental regulators. Recent studies indicate that many key regulatory genes are repressed in embryonic stem cells (ESCs), yet poised for rapid activation due to the presence of both act...

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Autori principali: Chakravarthy, Harini, Ormsbee, Briana D., Mallanna, Sunil K., Rizzino, Angie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005418/
https://ncbi.nlm.nih.gov/pubmed/20876214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-166926
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