EFFECT OF ANTICOMPLEMENT AGENT K76 COOH ON HAMSTER-TO-RAT AND GUINEA PIG-TO-RAT HEART XENOTRANSPLANTATION

In normal rats, the xenobiotic K76 inhibited the C5 and probably the C2 and C3 steps of complement and effectively depressed classical complement pathway activity, alternative complement pathway activity, and the C3 complement component during and well beyond the drug’s 3-hr half-life. It was tested...

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Main Authors: Tanaka, Mitsuko, Murase, Noriko, Ye, Qing, Miyazaki, Wasei, Nomoto, Minoru, Miyazawa, Hideaki, Manez, Rafael, Toyama, Yoichi, Demetris, Anthony J., Todo, Satoru, Starzl, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 1996
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005366/
https://ncbi.nlm.nih.gov/pubmed/8830837
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