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Rapid sampling of all-atom peptides using a library-based polymer-growth approach

We adapted existing polymer growth strategies for equilibrium sampling of peptides described by modern atomistic forcefields with a simple uniform dielectric solvent. The main novel feature of our approach is the use of pre-calculated statistical libraries of molecular fragments. A molecule is sampl...

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Detalhes bibliográficos
Main Authors: Mamonov, Artem B., Zhang, Xin, Zuckerman, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005036/
https://ncbi.nlm.nih.gov/pubmed/20734315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.21626
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