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Genes Involved in the Metabolism of Poly-Unsaturated Fatty-Acids (PUFA) and Risk for Crohn's Disease in Children & Young Adults

BACKGROUND AND OBJECTIVES: Epidemiological evidence for the role of polyunsaturated fatty-acids (PUFA) in Crohn's disease (CD) is unclear, although the key metabolite leucotriene B4 (LTB(4)) is closely linked to the inflammatory process. We hypothesized that inherited variation in key PUFA meta...

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Détails bibliographiques
Auteurs principaux: Costea, Irina, Mack, David R., Israel, David, Morgan, Kenneth, Krupoves, Alfreda, Seidman, Ernest, Deslandres, Colette, Lambrette, Philippe, Grimard, Guy, Levy, Emile, Amre, Devendra K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004960/
https://ncbi.nlm.nih.gov/pubmed/21187935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015672
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