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A Mitosis Block Links Active Cell Cycle with Human Epidermal Differentiation and Results in Endoreplication

How human self-renewal tissues co-ordinate proliferation with differentiation is unclear. Human epidermis undergoes continuous cell growth and differentiation and is permanently exposed to mutagenic hazard. Keratinocytes are thought to arrest cell growth and cell cycle prior to terminal differentiat...

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Hlavní autoři: Zanet, Jennifer, Freije, Ana, Ruiz, María, Coulon, Vincent, Sanz, J. Ramón, Chiesa, Jean, Gandarillas, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004957/
https://ncbi.nlm.nih.gov/pubmed/21187932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015701
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