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Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer

CONTEXT: Resveratrol exhibits colon cancer prevention activity in animal models; it is purported to have this activity in humans and inhibit a key signaling pathway involved in colon cancer initiation, the Wnt pathway, in vitro. DESIGN: A phase I pilot study in patients with colon cancer was perform...

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Autors principals: Nguyen, Anthony V, Martinez, Micaela, Stamos, Michael J, Moyer, Mary P, Planutis, Kestutis, Hope, Christopher, Holcombe, Randall F
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004662/
https://ncbi.nlm.nih.gov/pubmed/21188121
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