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Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats

Cancer pain is often difficult to treat. Growing evidence indicates that chemical mediators secreted by the tumor itself play an important role in the development of cancer pain. One such mediator, endothelin-1 (ET-1) is secreted by different tumor types. Studies have indicated that ET-1 induces spo...

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Detalhes bibliográficos
Main Authors: Hans, Guy, Deseure, Kristof, Vercauteren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004627/
https://ncbi.nlm.nih.gov/pubmed/21197295
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