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Ixabepilone development across the breast cancer continuum: a paradigm shift

The epothilone analog ixabepilone exhibits reduced susceptibility to several important tumor survival mechanisms that limit the efficacy of taxanes and anthracyclines. As a single agent, ixabepilone has shown promise in metastatic breast cancer when anthracyclines, taxanes, or capecitabine have fail...

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Detalhes bibliográficos
Autor principal: Ibrahim, Nuhad K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004591/
https://ncbi.nlm.nih.gov/pubmed/21188108
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