Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6

The three-dimensional structure of adeno-associated virus (AAV) serotype 6 (AAV6) was determined using cryo-electron microscopy and image reconstruction and using X-ray crystallography to 9.7- and 3.0-Å resolution, respectively. The AAV6 capsid contains a highly conserved, eight-stranded (βB to βI)...

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Hlavní autoři: Ng, Robert, Govindasamy, Lakshmanan, Gurda, Brittney L., McKenna, Robert, Kozyreva, Olga G., Samulski, R. Jude, Parent, Kristin N., Baker, Timothy S., Agbandje-McKenna, Mavis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004313/
https://ncbi.nlm.nih.gov/pubmed/20861247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01235-10
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