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Gene expression profiling of DEHP-treated cardiomyocytes reveals potential causes of phthalate arrhythmogenicity

BACKGROUND: Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer that imparts flexibility to polyvinyl chloride. We have recently reported that clinically relevant concentrations of DEHP can affect electrical coupling between cardiac myocytes causing significant rhythm disturbances. The u...

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Библиографические подробности
Главные авторы: Posnack, Nikki Gillum, Lee, Norman H., Brown, Ronald, Sarvazyan, Narine
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003946/
https://ncbi.nlm.nih.gov/pubmed/20920545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.09.007
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