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Gene expression profiling of DEHP-treated cardiomyocytes reveals potential causes of phthalate arrhythmogenicity

BACKGROUND: Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer that imparts flexibility to polyvinyl chloride. We have recently reported that clinically relevant concentrations of DEHP can affect electrical coupling between cardiac myocytes causing significant rhythm disturbances. The u...

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Detalhes bibliográficos
Main Authors: Posnack, Nikki Gillum, Lee, Norman H., Brown, Ronald, Sarvazyan, Narine
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003946/
https://ncbi.nlm.nih.gov/pubmed/20920545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.09.007
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