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Gene expression profiling of DEHP-treated cardiomyocytes reveals potential causes of phthalate arrhythmogenicity

BACKGROUND: Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer that imparts flexibility to polyvinyl chloride. We have recently reported that clinically relevant concentrations of DEHP can affect electrical coupling between cardiac myocytes causing significant rhythm disturbances. The u...

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Autors principals: Posnack, Nikki Gillum, Lee, Norman H., Brown, Ronald, Sarvazyan, Narine
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003946/
https://ncbi.nlm.nih.gov/pubmed/20920545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.09.007
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