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Gene expression profiling of DEHP-treated cardiomyocytes reveals potential causes of phthalate arrhythmogenicity

BACKGROUND: Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer that imparts flexibility to polyvinyl chloride. We have recently reported that clinically relevant concentrations of DEHP can affect electrical coupling between cardiac myocytes causing significant rhythm disturbances. The u...

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Main Authors: Posnack, Nikki Gillum, Lee, Norman H., Brown, Ronald, Sarvazyan, Narine
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003946/
https://ncbi.nlm.nih.gov/pubmed/20920545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.09.007
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