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Gene expression profiling of DEHP-treated cardiomyocytes reveals potential causes of phthalate arrhythmogenicity

BACKGROUND: Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer that imparts flexibility to polyvinyl chloride. We have recently reported that clinically relevant concentrations of DEHP can affect electrical coupling between cardiac myocytes causing significant rhythm disturbances. The u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Posnack, Nikki Gillum, Lee, Norman H., Brown, Ronald, Sarvazyan, Narine
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003946/
https://ncbi.nlm.nih.gov/pubmed/20920545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.09.007
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