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Thyrocyte interleukin-18 expression is up-regulated by interferon-γ and may contribute to thyroid destruction in Hashimoto's thyroiditis

Interferon-γ (IFN-γ) has a direct role in thyroid destruction in autoimmune thyroiditis. Interleukin-18 (IL-18), a pro-inflammatory cytokine with potent IFN-γ inducing activities, may play an important role in Th1-mediated autoimmune diseases. The purpose of this study was to characterize the expres...

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Detalhes bibliográficos
Main Authors: Liu, Zhe, Wang, Haining, Xiao, Wenhua, Wang, Chen, Liu, Guoqiang, Hong, Tianpei
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003839/
https://ncbi.nlm.nih.gov/pubmed/20586818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2010.00715.x
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