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Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment

INTRODUCTION: Glucocorticoids have extensively been used in the treatment of rheumatoid arthritis and other inflammatory diseases. However, their side-effects remain the major limitation in clinical use and an improved therapeutic index is needed. METHODS: Therapeutic efficacy and persistence of fre...

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Detalhes bibliográficos
Main Authors: Rauchhaus, Una, Schwaiger, Franz Werner, Panzner, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003516/
https://ncbi.nlm.nih.gov/pubmed/20003498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2889
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