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Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model

INTRODUCTION: The etiology of degenerative disc disease is unknown. Several investigators have reported the presence of proteolytic enzymes, such as the matrix metalloproteinase (MMP) and ADAMTS (a disintegrin and metalloprotease with thrombospondin-like repeats) families, in degenerated human discs...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Seki, Shoji, Asanuma-Abe, Yumiko, Masuda, Koichi, Kawaguchi, Yoshiharu, Asanuma, Kunihiro, Muehleman, Carol, Iwai, Akiko, Kimura, Tomoatsu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003501/
https://ncbi.nlm.nih.gov/pubmed/19889209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2851
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