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Altered Chaperone-like Activity of α-Crystallins Promotes Cataractogenesis
Despite the enormous number of studies demonstrating changes in the chaperone-like activity of α-crystallins in vitro, little is known about how these changes influence life-long lens transparency in vivo. Using the γB-crystallin I4F mutant protein as a target for αA-crystallins, we examined how cat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003416/ https://ncbi.nlm.nih.gov/pubmed/20959464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154534 |
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