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The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

Interaction of the pattern recognition receptor, RAGE with key ligands such as advanced glycation end products (AGE), S100 proteins, amyloid β, and HMGB1 has been linked to diabetic complications, inflammatory and neurodegenerative disorders, and cancer. To help answer the question of how a single r...

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Detalhes bibliográficos
Main Authors: Park, HaJeung, Boyington, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003376/
https://ncbi.nlm.nih.gov/pubmed/20943659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169276
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