Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions

Human embryonic stem cells (ESCs [hESCs]) proliferate as colonies wherein individual cells are strongly adhered to one another. This architecture is linked to hESC self-renewal, pluripotency, and survival and depends on epithelial cadherin (E-cadherin), NMMIIA (nonmuscle myosin IIA), and p120-cateni...

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Detalhes bibliográficos
Main Authors: Li, Dong, Zhou, Jiaxi, Wang, Lu, Shin, Myung Eun, Su, Pei, Lei, Xiaohua, Kuang, Haibin, Guo, Weixiang, Yang, Hong, Cheng, Linzhao, Tanaka, Tetsuya S., Leckband, Deborah E., Reynolds, Albert B., Duan, Enkui, Wang, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003326/
https://ncbi.nlm.nih.gov/pubmed/20974810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006094
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