Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

Many tumors contain heterogeneous populations of cells, only some of which exhibit increased tumorigenicity and resistance to anticancer therapies. Evidence suggests that these aggressive cancer cells, often termed “cancer stem cells” or “cancer stem-like cells” (CSCs), rely upon developmental signa...

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Detalles Bibliográficos
Main Authors: Fillmore, Christine M., Gupta, Piyush B., Rudnick, Jenny A., Caballero, Silvia, Keller, Patricia J., Lander, Eric S., Kuperwasser, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003123/
https://ncbi.nlm.nih.gov/pubmed/21098263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007863107
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