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Malignant cells facilitate lung metastasis by bringing their own soil

Metastatic cancer cells (seeds) preferentially grow in the secondary sites with a permissive microenvironment (soil). We show that the metastatic cells can bring their own soil—stromal components including activated fibroblasts—from the primary site to the lungs. By analyzing the efferent blood from...

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Detalhes bibliográficos
Main Authors: Duda, Dan G., Duyverman, Annique M. M. J., Kohno, Mitsutomo, Snuderl, Matija, Steller, Ernst J. A., Fukumura, Dai, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003109/
https://ncbi.nlm.nih.gov/pubmed/21098274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016234107
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