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Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells

Our previous studies of microperfused single proximal tubule showed that flow-dependent Na(+) and HCO(3)(−) reabsorption is due to a modulation of both NHE3 and vacuolar H(+)-ATPase (V-ATPase) activity. An intact actin cytoskeleton was indicated to provide a structural framework for proximal tubule...

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Autori principali: Duan, Yi, Weinstein, Alan M., Weinbaum, Sheldon, Wang, Tong
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003103/
https://ncbi.nlm.nih.gov/pubmed/21106755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015751107
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