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Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus

We describe a powerful system for revealing the direct monosynaptic inputs to specific cell types in Cre-expressing transgenic mice through the use of Cre-dependent helper virus and a modified rabies virus. We generated helper viruses that target gene expression to Cre-expressing cells, allowing us...

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Autori principali: Wall, Nicholas R., Wickersham, Ian R., Cetin, Ali, De La Parra, Mauricio, Callaway, Edward M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003023/
https://ncbi.nlm.nih.gov/pubmed/21115815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011756107
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