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The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

The cross-talk among cells of the innate immunity can greatly affect both innate and adaptive responses. Here we analyzed the molecular interactions between human natural killer (NK) cells and autologous macrophages. Activated NK cells killed M0 and M2, whereas M1 macrophages were more resistant to...

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Detalhes bibliográficos
Main Authors: Bellora, Francesca, Castriconi, Roberta, Dondero, Alessandra, Reggiardo, Giorgio, Moretta, Lorenzo, Mantovani, Alberto, Moretta, Alessandro, Bottino, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003022/
https://ncbi.nlm.nih.gov/pubmed/21118979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007654108
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