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Combining Network Modeling and Gene Expression Microarray Analysis to Explore the Dynamics of Th1 and Th2 Cell Regulation

Two T helper (Th) cell subsets, namely Th1 and Th2 cells, play an important role in inflammatory diseases. The two subsets are thought to counter-regulate each other, and alterations in their balance result in different diseases. This paradigm has been challenged by recent clinical and experimental...

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Detalhes bibliográficos
Main Authors: Pedicini, Marco, Barrenäs, Fredrik, Clancy, Trevor, Castiglione, Filippo, Hovig, Eivind, Kanduri, Kartiek, Santoni, Daniele, Benson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002992/
https://ncbi.nlm.nih.gov/pubmed/21187905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001032
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