Rat Hypocretin/Orexin Neurons Are Maintained in a Depolarized State by TRPC Channels

In a previous study we proposed that the depolarized state of the wake-promoting hypocretin/orexin (hcrt/orx) neurons was independent of synaptic inputs as it persisted in tetrodotoxin and low calcium/high magnesium solutions. Here we show first that these cells are hyperpolarized when external sodi...

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Main Authors: Cvetkovic-Lopes, Vesna, Eggermann, Emmanuel, Uschakov, Aaron, Grivel, Jeremy, Bayer, Laurence, Jones, Barbara E., Serafin, Mauro, Mühlethaler, Michel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002943/
https://ncbi.nlm.nih.gov/pubmed/21179559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015673
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