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Discontinuous pH gradient-mediated separation of TiO(2)-enriched phosphopeptides

Global profiling of phosphoproteomes has proven a great challenge due to the relatively low stoichiometry of protein phosphorylation and poor ionization efficiency in mass spectrometers. Effective, physiologically-relevant, phosphoproteome research relies on the efficient phosphopeptide enrichment f...

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Detalhes bibliográficos
Main Authors: Park, Sung-Soo, Maudsley, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002755/
https://ncbi.nlm.nih.gov/pubmed/20946866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.10.003
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