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Population Genetic Analysis of the Uncoupling Proteins Supports a Role for UCP3 in Human Cold Resistance

Production of heat via nonshivering thermogenesis (NST) is critical for temperature homeostasis in mammals. Uncoupling protein UCP1 plays a central role in NST by uncoupling the proton gradients produced in the inner membranes of mitochondria to produce heat; however, the extent to which UCP1 homolo...

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Autors principals: Hancock, Angela M., Clark, Vanessa J., Qian, Yudong, Di Rienzo, Anna
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002247/
https://ncbi.nlm.nih.gov/pubmed/20802238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq228
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