Cadmium Alters the Biotransformation of Carcinogenic Aromatic Amines by Arylamine N-Acetyltransferase Xenobiotic-Metabolizing Enzymes: Molecular, Cellular, and in Vivo Studies

BACKGROUND: Cadmium (Cd) is a carcinogenic heavy metal of environmental concern. Exposure to both Cd and carcinogenic organic compounds, such as polycyclic aromatic hydrocarbons or aromatic amines (AAs), is a common environmental problem. Human arylamine N-acetyltransferases (NATs) are xenobiotic-me...

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Autores principales: Ragunathan, Nilusha, Dairou, Julien, Sanfins, Elodie, Busi, Florent, Noll, Christophe, Janel, Nathalie, Dupret, Jean-Marie, Rodrigues-Lima, Fernando
Formato: Artigo
Lenguaje:Inglês
Publicado: National Institute of Environmental Health Sciences 2010
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002187/
https://ncbi.nlm.nih.gov/pubmed/20810355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002334
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