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Cardiac Glycosides Ouabain and Digoxin Interfere with the Regulation of Glutamate Transporter GLAST in Astrocytes Cultured from Neonatal Rat Brain

Glutamate transport (GluT) in brain is mediated chiefly by two transporters GLT and GLAST, both driven by ionic gradients generated by (Na(+), K(+))-dependent ATPase (Na(+)/K(+)-ATPase). GLAST is located in astrocytes and its function is regulated by translocations from cytoplasm to plasma membrane...

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Detalhes bibliográficos
Main Authors: Nguyen, Khoa T. D., Buljan, Vlado, Else, Paul L., Pow, David V., Balcar, Vladimir J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002169/
https://ncbi.nlm.nih.gov/pubmed/20890657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-010-0274-4
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