CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex

CDK5RAP2 is a human microcephaly protein that contains a γ-tubulin complex (γ-TuC)–binding domain conserved in Drosophila melanogaster centrosomin and Schizosaccharomyces pombe Mto1p and Pcp1p, which are γ-TuC–tethering proteins. In this study, we show that this domain within CDK5RAP2 associates wit...

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Main Authors: Choi, Yuk-Kwan, Liu, Pengfei, Sze, Siu Kwan, Dai, Chao, Qi, Robert Z.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002024/
https://ncbi.nlm.nih.gov/pubmed/21135143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007030
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