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BCR-ABL mutation testing to predict response to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML). Although randomized evidence demonstrates that imatinib (a commercially available TKI) prolongs event–free survival in patients with CML, some patients develop imatinib intolerance or resistance. I...

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Detalhes bibliográficos
Main Authors: Terasawa, Teruhiko, Dahabreh, Issa, Trikalinos, Thomas A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001986/
https://ncbi.nlm.nih.gov/pubmed/21188137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1204
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