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BCR-ABL mutation testing to predict response to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML). Although randomized evidence demonstrates that imatinib (a commercially available TKI) prolongs event–free survival in patients with CML, some patients develop imatinib intolerance or resistance. I...

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Bibliografiske detaljer
Main Authors: Terasawa, Teruhiko, Dahabreh, Issa, Trikalinos, Thomas A
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001986/
https://ncbi.nlm.nih.gov/pubmed/21188137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1204
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