Uterine Epithelial Cell Regulation of DC-SIGN Expression Inhibits Transmitted/Founder HIV-1 Trans Infection by Immature Dendritic Cells

BACKGROUND: Sexual transmission accounts for the majority of HIV-1 infections. In over 75% of cases, infection is initiated by a single variant (transmitted/founder virus). However, the determinants of virus selection during transmission are unknown. Host cell-cell interactions in the mucosa may be...

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Main Authors: Ochiel, Daniel O., Ochsenbauer, Christina, Kappes, John C., Ghosh, Mimi, Fahey, John V., Wira, Charles R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001862/
https://ncbi.nlm.nih.gov/pubmed/21179465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014306
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